Ceramic film technology application for cleaner production in biopharmaceutical industry


With the continuous development of membrane technology, the use of membrane separation technology in the biopharmaceutical field is not uncommon. It has the characteristics of easy operation, energy saving, and does not cause new environmental pollution, especially in the extraction of active ingredients of biopharmaceuticals, protoplasm, microbial separation and recovery, clarification and other processes, membrane separation is one of the essential technologies.

Ceramic membrane has the characteristics of corrosion resistance, high temperature resistance and high separation accuracy, and membrane separation technology with ceramic membrane as the core has become the preferred high-efficiency separation technology in the biological and pharmaceutical industries. At present, in the biopharmaceutical industry, relevant departments have taken "inorganic ceramic combined membrane separation technology" as a clean production process technology to promote in the fermentation antibiotic and vitamin pharmaceutical industry.


Ceramic membrane separation is a screening process related to pore size, using dynamic cross-flow filtration: the raw material liquid through the circulation pump in the ceramic membrane pore for high-speed circulation movement, under the action of pressure, the clarified permeate through the ceramic diaphragm and porous ceramic matrix, along the perpendicular direction to the membrane outward through the membrane, the concentrate is intercepted by the membrane, and in the pores for high-speed flow and cause turbulence, constantly rinse the inner surface of the ceramic diaphragm, and take away a small amount of sediment attached to the filter membrane. Maintain a stable outflow of clear liquid, so that the fluid can achieve the purpose of separation, concentration and purification.

In view of the current status of biomedical development, it is necessary to enhance the ability of technological innovation and product innovation, and gradually form China's superior technologies and products in the field of biomedicine. Ceramic membrane has the characteristics of low energy consumption, high efficiency and non-inactivation of bioactive substances, and has been widely used in the field of biomedicine in recent years.